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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T38514 | PMEDAP | Others , HIV Protease | |
PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomega... | |||
T11669 | IR415 | HBV | |
T38237 | 2′-O-Methylcytidine | Nucleoside Antimetabolite/Analog , HCV Protease | |
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G.... | |||
T11539 | HCV-IN-29 | HCV Protease | |
HCV-IN-29 is a hepatitis C virus (HCV) inhibitor. | |||
T11541 | HCV-IN-30 | Others , HCV Protease | |
HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons). | |||
T9212 | IMB-301 | Others , HIV Protease | |
IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model. | |||
T8354 | Triazavirin | Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis | |
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. | |||
T8371 | ML188 | Virus Protease , SARS-CoV | |
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity. | |||
T11538 | Hck-IN-1 | HIV Protease , Src , Hck | |
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w... | |||
T11281L | FGI-106 tetrahydrochloride | Virus Protease , HCV Protease , Influenza Virus , HIV Protease | |
T7330 | Nucleozin | Influenza Virus | |
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. | |||
T14968 | Cinanserin hydrochloride | SQ 10643 | Influenza Virus , 5-HT Receptor |
Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. | |||
T9716 | Ensitrelvir | S-217622 | SARS-CoV |
Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM. | |||
T14495 | Baloxavir | Baloxavir acid,S-033447 | Influenza Virus |
Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. | |||
T0220 | Foscarnet sodium | Phosphonoformate | Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis |
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV. | |||
T9350 | IMP-1088 | Others , DNA/RNA Synthesis | |
IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual. | |||
T1623 | Lopinavir | ABT-378 | SARS-CoV , HIV Protease |
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr... | |||
T6439 | Cetylpyridinium Chloride | Cetamium,Pristacin,Hexadecylpyridinium Chloride | Others , HBV , Antibacterial |
Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic. | |||
T9567 | Samatasvir | ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719 | HCV Protease |
Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A. | |||
T4686 | Simeprevir | TMC435,TMC-435350,Olysio | HCV Protease , SARS-CoV |
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM. | |||
T7055 | Bz-RS-ISer(3-Ph)-Ome | Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate | Others , HIV Protease |
Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o... | |||
T0688 | Ganciclovir | BW 759,RS-21592,2'-Nor-2'-deoxyguanosine | Nucleoside Antimetabolite/Analog , Others , Antibiotic , Antifection , HSV |
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegaloviru... | |||
T9854 | HIV-1 inhibitor-6 | 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- | HIV Protease |
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication. | |||
T22337 | Ganciclovir sodium | RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium | Nucleoside Antimetabolite/Analog , Others , Antifection , HSV |
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1). | |||
T9331 | Bemnifosbuvir hemisulfate | AT-527 | HCV Protease , SARS-CoV |
Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication. | |||
T67753 | Trifluoromethyl-tubercidin | Influenza Virus | |
Trifluoromethyl-tubercidin (TFMT) inhibits host MTr1 and suppresses virus replication. TFMT inhibits MTr1 through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication. TFMT wa... | |||
T67854 | BAS 00489700 | Others | |
BAS 00489700 is a N-UTR interaction inhibitor. BAS 00489700 inhibits virus replication in cell culture. | |||
T6244 | Cidofovir | HPMPC,GS 0504,(S)-HPMPC | Others , DNA/RNA Synthesis |
Cidofovir ((S)-HPMPC) inhibits virus replication by specific inhibition of viral DNA synthesis. | |||
T29187 | YM-53403 | ||
YM-53403 is an antiviral activity that effectively inhibits the replication of RSV strains belonging to subgroup A and subgroup B. It can be used to treat respiratory syncytial virus infections. | |||
T17190 | U18666A | Others , HCV Protease | |
U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus. | |||
T1822L | Clemizole hydrochloride | HCV Protease , Histamine Receptor | |
Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replication and NS4B's RNA binding. | |||
T0085 | Entecavir monohydrate | SQ 34676,BMS-200475,Entecavir hydrate | HBV |
Entecavir monohydrate (BMS-200475) is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog. | |||
T1822 | Clemizole | HCV Protease , Histamine Receptor | |
Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. | |||
T38238 | 2'-Deoxy-2'-fluorocytidine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o... | |||
T50031 | Virstatin | Others | |
Virstatin is a novel antiviral drug that is a potent inhibitor of viral replication . It has been shown to be effective against a wide range of viruses, including herpes simplex virus (HSV), human immunodeficiency virus ... | |||
T3489 | Dasabuvir | ABT-333 | HCV Protease |
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra... | |||
T23819 | Braco-19 trihydrochloride | BRAC-O19,BRACO19 hydrochloride,BRACO19 3HCl,BRACO 19,BRACO19 HCl | Telomerase |
Braco-19 trihydrochloride (BRACO19 3HCl) is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV virus replication. | |||
T11025 | HDHODH-IN-3 | DHODH-IN-2 | Dehydrogenase |
hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication. | |||
T26987 | CF-1743 | CF1743 | HSV |
CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication. CF-1743 can be used in studies about infection of varicella and herpes zoster. | |||
T26674 | AT-130 | AT 130 | HBV , DNA/RNA Synthesis |
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging. | |||
T15280 | Fiacitabine | FOAC,FIAC,NSC 382097 | HSV |
Fiacitabine (NSC-382097) is a selective inhibitor of DNA replication of the herpes simplex virus(HSV) (IC50: 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively). | |||
T38236 | 2′-Deoxy-2′-fluoroguanosine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respirator... | |||
T14044 | 4E2RCat | PERK | |
T9249 | ITMN4077 | Antiviral | |
ITMN4077 has antiviral activity against Hepatitis C virus infected in human HuH7 cells assessed as inhibition of HCV subgenomic replicon replication with an EC50 of 2.131μM. | |||
T25770 | 116-9e | MAL-2-11B,MAL2-11B,MAL211B,MAL 2 11B,MAL2 11B | Virus Protease |
116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibition of simian virus 40 (SV40) replication, inhibition of tumour antigen (TAg) endogenous ATPase activity, and TAg-mediat... | |||
T11028 | HDHODH-IN-4 | DHODH-IN-5 | Dehydrogenase |
hDHODH-IN-4 (DHODH-IN-5) is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. hDHODH-IN-4 inhibits measles virus replication with a pMIC50 of 8.8. | |||
T26619 | Amitivir | LY217896,LY 217896,LY-217896 | Others , Influenza Virus |
Amitivir (LY 217896) is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffe... | |||
T15704 | Lagociclovir | MIV-210 | HBV |
Lagociclovir (MIV-210), a nucleoside analogue, is an antiviral compound available for the treatment of HBV82 that inhibits the replication of wild-type hepatitis B virus (HBV) in human hepatocellular carcinoma cell lines... | |||
T25130 | Azaribine | 2',3',5'-Tri-O-acetyl-6-azauridine,NSC 67239 | Antiviral |
Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) is an orotate monophosphate decarboxylase (OMPD) inhibitor with broad-spectrum antiviral activity, inhibiting viral genome replication and gene transcription.Azaribine has b... | |||
T9394 | CHIKV-IN-2 | Dehydrogenase | |
CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effec... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN2283 | Tripterifordin | HIV Protease | |
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml. | |||
T5429 | Theaflavin 3,3'-digallate | 8-Gingerol,TFDG | Virus Protease , Antioxidant , HIV Protease , HSV |
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul... | |||
T6S2391 | L-Chicoric Acid | (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid | Others , HIV Protease |
L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ... | |||
T3905 | Isomangiferin | Free radical scavengers , Antiviral , Influenza Virus | |
Isomangiferin has an antiviral effect, may due to their capability of inhibiting virus replication within cells. It also has antioxidant and radical-scavenging activities. | |||
TL0006 | Cichoric Acid | Dicaffeoyltartaric acid,Chicoric Acid | Reactive Oxygen Species , HIV Protease |
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ... | |||
T0884 | 1-Docosanol | Behenic alcohol,Behenyl alcohol,n-Docosanol,Docosanol | Antifection , HSV |
1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex viru... | |||
TN3500 | Beta-Amyrone | β-Amyron | COX , AChR , PPAR , Antifection |
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a... | |||
T26111 | Robustaflavone | ||
Robustaflavone is a naturally occurring biflavanoid isolated from Rhus succedanea and is a hepatitis B virus replication inhibitor. | |||
TN6395 | Citrusin B | ||
Citrusin B exhibits moderate in vitro inhibitory effect on tobacco mosaic virus replication with IC50 values 0.26 mmol L⁻1. | |||
T17270 | Yatein | Others | |
Yatein inhibits herpes simplex virus type 1 replication by interruption the immediate-early gene expression. Yatein is a lignan isolated from A. chilensis. It also has antiproliferative activity. | |||
TN2231 | Soyasaponin II | Influenza Virus , HIV Protease , HSV | |
Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1. | |||
TN1632 | Euparin | Antifection | |
Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication ... | |||
TN3809 | Dehydrojuncusol | HCV Protease | |
Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is active against resistant HCV variants frequently found in patie... | |||
T80002 | Wulfenioidin F | Virus Protease | |
Wulfenioidin F, a diterpenoid isolated from the whole plant of Orthosiphon wulfenioides, exhibits anti-Zika virus (ZIKV) activity with an EC50 of 8.07 μM and hinders virus replication by inhibiting the expression of the ... | |||
T36489 | Malformin A | ||
Malformin A is a cyclopentapeptide fungal metabolite that has been found in A. niger and has diverse biological activities. It is a plant growth regulator that induces malformations in plant structure. Malformin A inhib... | |||
T83693 | Magainin 2 TFA | MG2 | |
Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pne... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-04870 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 protein (His) | ZIKV | HEK293 Cells |
Zika virus NS1 antigen is one of seven non-structural proteins. NS1 is involved in RNA replication. The possible effects of NS1 on hosts include: localizes to host cell surface and secreted extracellularly, modulates sig... | |||
TMPY-03758 | Vaccinia Virus B18R/B19R Protein (His) | VACV | Baculovirus Insect Cells |
B18R is a type I interferon (IFN)-binding protein, which is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus. It is also known as B19R in the Copenhagen strain of Vaccinia. ... | |||
TMPY-02841 | Fragilis/IFITM3 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interf... | |||
TMPH-03416 | Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO) | RVFV | E. coli |
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. After replication, the nucleocapsid is recr... | |||
TMPH-00367 | Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (His & SUMO) | CAV | E. coli |
May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (His & SUMO) is expressed in E. coli e... | |||
TMPH-00366 | Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (GST) | CAV | E. coli |
May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (GST) is expressed in E. coli expressi... | |||
TMPH-02382 | Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO) | MARV | E. coli |
Plays an essential role virus particle assembly and budding. Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 ... | |||
TMPK-01252 | E8L Protein, Monkeypox virus, Recombinant (His) | Monkeypox virus | E. coli |
E8L is an important protein that mediates the invasion of monkeypox virus into host cells. In the process of invading and completing replication, E8L acts as a surface-binding protein of mature virion and can bind to cho... | |||
TMPH-01673 | Human metapneumovirus (strain CAN97-83) Matrix protein (His) | HMPV | P. pastoris (Yeast) |
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti... | |||
TMPY-04904 | Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc) | ZIKV | HEK293 Cells |
Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibit... | |||
TMPK-01192 | Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His) | Varicella-zoster virus (strain Oka vaccine) | HEK293 Cells |
VZV glycoprotein E (gE) is most abundantly expressed on the surface of infected cells, and is an essential component for virus replication and cell-to-cell transmission. It is also the main target of virus-specific antib... | |||
TMPH-01248 | ADAR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... | |||
TMPH-01843 | Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His) | HPIV-4b | E. coli |
Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replica... | |||
TMPH-00810 | Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) | HDV | P. pastoris (Yeast) |
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging ... | |||
TMPH-00365 | Chicken anemia virus (isolate USA 26p4) Apoptin Protein (His) | CAV | E. coli |
May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate USA 26p4) Apoptin Protein (His) is expressed in E. coli expression system ... | |||
TMPH-01672 | Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc) | HMPV | E. coli |
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti... | |||
TMPH-02346 | Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc) | H1N1 | E. coli |
Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction... | |||
TMPY-02285 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein | H1N1 | E. coli |
Non-structural protein 2 (NS2) plays a crucial role in the hepatitis C virus (HCV) assembly. NS2 was predicted to be composed of three transmembrane (TM) segments. Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is... | |||
TMPH-01841 | Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His) | HPIV-1 | E. coli |
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for trans... | |||
TMPH-03226 | Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST) | RABV | E. coli |
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates... | |||
TMPH-00811 | Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc) | HDV | P. pastoris (Yeast) |
Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II th... | |||
TMPH-00545 | Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc) | EBV | E. coli |
Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial ... | |||
TMPY-05693 | SARS-CoV-2 Methyltransferase/ME Protein (His) | SARS-CoV-2 | E. coli |
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate... | |||
TMPK-01298 | BST2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune res... | |||
TMPH-03225 | Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc) | RABV | E. coli |
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates... | |||
TMPH-00028 | Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) | AAV-2 | E. coli |
Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a... | |||
TMPH-02347 | Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His) | H1N1 | E. coli |
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of th... | |||
TMPH-01522 | HIV-2 (subtype A, isolate ROD) Protein Vpx (His) | HIV-2 | P. pastoris (Yeast) |
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by... | |||
TMPH-02348 | Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc) | H1N1 | E. coli |
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of th... | |||
TMPY-00818 | Granzyme H/GZMH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes... | |||
TMPY-00729 | Cystatin D Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stef... | |||
TMPH-03733 | Zaire ebolavirus (strain Kikwit-95) VP35 Protein (His & Myc) | ZEBOV | HEK293 Cells |
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/... | |||
TMPH-03732 | Zaire ebolavirus (strain Kikwit-95) VP35 Protein (E. col, His & Myc) | ZEBOV | E. coli |
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/... | |||
TMPH-02841 | Prohibitin Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regul... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L1720 | Nucleotide Compound Library | 334 compounds | |
A unique collection of 334 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; |